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Wednesday, April 2, 2025

Engineering an Open Supply CRISPR with Aadyot Bhatnagar


CRISPR is a strong instrument in biotechnology that enables scientists to exactly edit genes, very like modifying strains of code in a pc program. Simply as builders can take away or alter particular components of a code to repair bugs or improve performance, CRISPR allows researchers to switch DNA to appropriate genetic issues, enhance crops, or develop new therapies. The event of CRISPR-based modifying was acknowledged by the Nobel Prize in Chemistry in 2020 awarded to Emmanuelle Charpentier and Jennifer Doudna.

Profluent Bio is an AI-first protein design firm that not too long ago developed OpenCRISPR-1, which is an AI-generated, CRISPR-like protein that doesn’t happen in nature. Importantly, the corporate additionally launched the protein and nucleic acid sequences for OpenCRISPR-1.

Aadyot Bhatnagar is an ML Scientist at Profluent Bio and beforehand labored at Salesforce. He joins the podcast with Sean Falconer to speak about OpenCRISPR-1 and the way it was made.

Sean’s been an educational, startup founder, and Googler. He has printed works overlaying a variety of matters from info visualization to quantum computing. Presently, Sean is Head of Advertising and marketing and Developer Relations at Skyflow and host of the podcast Partially Redacted, a podcast about privateness and safety engineering. You may join with Sean on Twitter @seanfalconer.

 

 

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